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Gene deletion of glutathione S-transferase theta: correlation with induced genetic damage and potential role in endogenous mutagenesis

This study looked aerobic and resistance exercise regimens for people with NAFLD and found similar outcomes in reducing hepatic steatosis but lower total energy consumption in those who completed resistance exercise

Others argue that the doctors prescribed the drug without proper evaluation

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A 2026 review in the British Journal of Pharmacology identified weight-loss plateaus as one of the persistent challenges of GLP-1 therapy, noting that counter-regulatory systems, including the endocannabinoid system, actively resist further loss [3]

Multiple CV outcomes trials (CVOTs) have provided strong evidence that GLP-1RAs reduce ASCVD events (5057), although the mechanisms remain multifaceted and are still under investigation