146 The pathophysiology of addiction has been extensively investigated, revealing drug-induced dysregulation of multiple neural circuits and neurochemical systems, including dopamine, opioid peptides, corticotropin-releasing factor, dynorphin, glutamate, and gamma-aminobutyric acid (GABA)
Current evidence is limited to preclinical animal studies, making its use speculative and experimental
The only thing that changed is the concentration
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doi:10.1016/0361-9230(86)90111-5 Scherschlicht R, Aeppli L, Polc P, Haefely W
When they do occur, we address them through meal timing, food composition, portion adjustments, and supporting medications when necessary