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Mitochondrial -oxidation of VPA involves its transport within 2 the mitochondrial matrix, using the same pathway as do long-chain fatty acids

Its main job is to sweep up "free radicals", unstable molecules that cause damage to your cells, a process known as oxidative stress

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Tumor volume decreased from 155 mm 3 to 84 mm 3 for Patient 3 and from 7,150 mm 3 to 4,389 mm 3 for Patient 4

doi: 10.1038/cr.2010.178 86 KimSEKimJLeeJYLeeSBPaikJSYangSW

Such cases of neurologic progression in vitamin B 12 deficiency have been mostly seen in case studies at folic acid doses of 5,000 g (5 mg) and above