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Avoid taking Ozempic if you have: A history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, or diabetic retinopathy

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Tirzepatide, a dual glucagon-like peptide-1 (GIP) and GLP-1RAs, administered once weekly at a 15 mg dose, resulted in an average weight loss of 20.9% over 72 weeks (Jastreboff et al., 2022), driven by its synergistic effects on appetite regulation, energy intake reduction, and fat mass decrease (Heise et al., 2023)

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Mild cases caused by hemorrhoids or anal fissures may be managed conservatively, while severe bleeding due to diverticulosis, inflammatory bowel disease, or malignancies often requires urgent endoscopic or surgical intervention