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In DXA body-composition analyses from the STEP 1 semaglutide program and the SURMOUNT-1 tirzepatide trial, lean mass decreased alongside fat mass, and the STEP 1 extension showed that many participants regained about two-thirds of their lost weight after stopping semaglutide, which is one more reason to protect muscle and training habits while the medication is working

A racing heart, restlessness, or difficulty relaxing can feel overwhelming, especially for someone already prone to anxiety

What additional laboratory tests would be helpful

GLP-1 MODULATES LIPID METABOLISM GLP-1 Modulates fat synthesis in the liver GLP-1 modulates hepatic lipolysis GLP-1 modulates liver cholesterol metabolism GLP-1 modulates adiposynthetic and differentiation GLP-1 modulates fat browning Clinical application of GLP-1 in obesity Obesity is a major health problem worldwide

Many patients report nausea, early fullness, and reduced appetite

McCann, S