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Although several screening tools and neuropsychological tests were developed 2,12,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31 , brain functional imaging methods for patients with covert hepatic encephalopathy were not established in daily clinical settings

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Meanwhile, L-carnitine exerts an inhibitory effect on matrix metalloproteinases MMP-1 and MMP-2 , demonstrated in studies in vitro

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This was evidenced by the increased presence of macrophages and CD8 + T cells, along with elevated mRNA expression levels of IL-2, IL-12, IL-10, TNF-, IFN-, and programmed death ligand-1 (PD-L1) in the site of the tumor

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