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Similarly, it improved cerebral energy metabolism in ischemic rat brain (Suzuki et al., 2001) and prevented glutamate mediated neuronal toxicity and lipid peroxidation (Meja-Toiber et al., 2006)

Six axes of molecular activity of the peptide have been described in the preclinical literature with the best documented modulation of the VEGF/VEGFR2 pathway (angiogenesis) and the FAK-paxillin cascade (fibroblast migration) as well as protection of the mucosa and the brain-gut axis important in the oral form

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Research published in peptide science journals indicates KPV demonstrates notable anti-inflammatory properties at the cellular level

References: National Institute for Health and Care Excellence (NICE)

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