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Moderate pain lasting more than 3 weeks, or severe pain that limits function, warrants immediate communication with your care providerthese may signal that your dose pace is too aggressive for your individual physiology

In 2023, a record 10,660 liver transplants were performed in the United States alone, with MASH accounting for 27% of these procedures, making it the second leading indication for liver transplantation

The mainstay of treatment is levothyroxine replacement therapy , which aims to restore normal thyroid hormone levels

Drawing a dose into a syringe and storing it for later is not recommended

Obesity is increasingly framed as part of a continuum of metabolic disease , rather than as a separate condition

However, further studies are warranted to fully delineate the distinct pathophysiology of MetALD development, which is driven by both alcohol and metabolic dysfunction