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Aging cells cannot be stimulating proliferation, it is by a variety of types of damage and stress caused by, not due to terminal differentiation, its characteristic is that through the cell cycle dependent kinase inhibitor p16 and p21CIP1, results in the stagnation of irreversible cell cycle (21)

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Singh VP, Singh S, Kumar J, Prasad SM

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10.1016/s0140-6736(16)32453-32459 Lancet 15 BuurmanR.GurlevikE.SchafferV.EilersM.SandbotheM.KreipeH.et al (2012)

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