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The selectivity data come primarily from rat pituitary cell studies and a small number of animal in vivo experiments

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After SLC7A11 siRNA transfection or miR-429 mimicry, the antioxidative stress and anti-ferroptosis effects of HSYA were reduced

AP-1, NFB and Nrf2 are all positive regulators of the rat GCLM gene and are induced by TNF treatment (Yang et al., 2005b)

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