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The increase of L-carnitine in plasma via oral administration, even up to and exceeding 2 mg, is limited, since L-carnitine has a very poor absorption and bioavailability, a very high renal clearance, and active uptake into tissues

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Vilario-Garca T, Polonio-Gonzlez M, Prez-Prez A, Ribalta J, Arrieta F, Aguilar M, et al

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Limitations of Available Evidence Research varies based on study design, dosing, and delivery method

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