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In response to various stimuli, including ROS, inflammatory mediators, mechanical forces, and catecholamines, endothelial cells release chemokines, and adhesion molecules, such as ICAM-1 and vascular cell adhesion molecule (VCAM)-1

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A general increase in ROS and free radicals in the aged brain and a phenomenon known as niche stiffening of the extracellular matrix (ECM) directly adjacent to OPCs can also prevent their differentiation (French et al., 2009

This raised interest in whether human metallothioneins, which are highly reactive and Cys-rich, undergo S-thioallylation by GOSC (Fig

10.1128/aac.32.12.1763 Antimicrob