Ameliorative effect of rubiadin-loaded nanocarriers in STZ-NA-induced diabetic nephropathy in rats: formulation optimization, molecular docking, and in vivo biological evaluation
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However, overexpression of myo-inositol oxygenase (MIOX) can aggravate cisplatin-induced ferroptosis in the context of AKI by downregulating GPX4 activity, promoting lipid peroxidation and increasing the ferritinophagy rate [172]
Pro-inflammatory cytokines, particularly those belonging to the interleukin-1 (IL-1) family and tumor necrosis factor-alpha (TNF-), can promote lipolysis and lipid transport by upregulating hormone-sensitive lipase (HSL) and inhibiting peroxisome proliferator-activated receptor gamma (PPAR-)
doi: 10.3389/fimmu.2020.01748 51 DaiJ.WangY.WangH.GaoZ.WangY.FangM.et al
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