Specifically, these mechanisms of action cover multiple aspects, such as activation of the cAMP-PKA signaling pathway, inhibition of pro-inflammatory cytokine release, and also activation of the AMPK signaling pathway, promoting the expression of anti-inflammatory genes, and regulation of macrophage function [26]
This has not been reported in previous studies
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Diabetes Care 35:252258 Knudsen LB, Nielsen PF, Huusfeldt PO et al (2000) Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration
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