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Low caloric intake can lead to: Low blood sugar variability Increased cortisol Reduced serotonin production All of these can show up as irritability, impatience, or emotional reactivity

Direct effects on blood vessels: Some research suggests GLP-1 receptors in the eye may influence local blood flow

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A study of Retatrutide (LY3437943) in the maintenance of weight reduction in Individuals with obesity Summary: This ongoing Phase 3 study aims to evaluate how retatrutide maintains body weight loss in participants with obesity