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Diets high in fat and carbohydrates can alter the microbiome, potentially leading to overproduction of GIP and increased fat storage

This issue should be evaluated separately from the gastrointestinal injury claims centralized in MDL No

Peter : Yeah, so that might offset it

Cost and accessibility are also important factors

Approved by the FDA in November 2023 for chronic weight management, Zepbound is the first and only dual receptor agonist available for obesity treatment

Acknowledgements We are grateful to Wenxin Li, Wenbo Feng, Chenyu Ye, Yingna Xu, Yan Chen, Xianyue Chen, Jiahui Yan and Qiuying Wang for technical assistance