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Pyloric injection of botulinum toxin for treatment of diabetic gastroparesis

Results: The percent of individuals achieving the exposure target at the time of first PK collection was higher in subjects receiving initial doses provided by the model-informed precision dosing platform (cohort C, 75%) versus subjects receiving initial doses based on either of the two other approaches (conventional guidelines/cohort A, 25%

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This can be due to lower folate intake in these subjects