Pre-start checklist Before your first injection, these items need to be completed: Thyroid function optimized: Your TSH should be within your optimal range (not just "normal," but where you feel best, often in the lower half of the reference range for Hashimoto's patients)
Reference Mozaffarian, D., Agarwal, M., Aggarwal, M., et al
In patients who are not tolerant to Metformin, GLP-1 drugs can be prescribed as an alternative from the start
1,5 Because of minimal gastrointestinal (GI) absorption and less oral bioavailability, these drugs are available in subcutaneous injectable form, except for semaglutide, which is available both in oral and injectable forms
For most patients, fatigue improves within several weeks to a few months as the body adapts to treatment
They are generally safe for most people, but not recommended for individuals with a history of medullary thyroid cancer, MEN2, pancreatitis, severe kidney or liver disease, or those who are pregnant or breastfeeding. What are the most common side effects of GLP-1 drugs