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Group A Streptococcus Co-Ordinates Manganese Import and Iron Efflux in Response to Hydrogen Peroxide Stress

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Conclusion Intraventricular administration of streptozotocin (3 mg/kg, single bilateral injection) induces not only neuronal damage but also reactive astroglial changes, pronounced tanycyte degeneration, disruption of the ependymal lining in the third and lateral ventricles, astrocytic dysfunction, and altered distribution of aquaporin-4 and connexin-43 in hypothalamic structures

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