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Chen Y, BrennanMinnella AM, Sheth S, ElBenna J, Swanson RA

When stored at room temperature, the active compound breaks down gradually, reducing its ability to activate GLP-1 receptors and trigger appetite suppression

The LR3 modification adds a 13-amino-acid extension and replaces one amino acid, which reduces binding to the proteins that normally deactivate IGF-1 in your bloodstream

Other similar weight loss drugs like Mounjaro or Saxenda are also GLP-1 RAs, but they have different active ingredients

Patients are advised to seek immediate help if they experience overdose symptoms like persistent nausea or vomiting

Some people find their symptoms improve significantly with weight loss, but medication is usually still necessary