The activation of the classical cAMP pathway is achieved by releasing irritating G protein subunit Gs through the exchange of guanine nucleotide and the activation/dissociation of heterogeneous trimer G protein, and in pancreatic cells, GLP-1 binds to the specific guanine nucleotide-binding protein-coupled receptor GLP-1R, leading to adenylyl cyclase activation and elevated cAMP levels (Mayo et al., 2003
So it's not just appetite control, it's actually beneficial throughout the body, and that we didn't see that one coming
To date, they represent the only G protein-coupled receptor (GPCR) ligands approved as glucose-lowering agents (2)
The Honest GLP-1 Guide: What Most People Arent Told About GLP-1 Therapy, Muscle Loss, Plateaus, and Long-Term Metabolic Health - Kindle edition by Alozie, Sylvalene
More options generally mean better ability to customize your protocol
I also like that I can get so many boxes checked in one visit