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The hormone-regulating benefits come from restored insulin sensitivity and reduced inflammation, which secondarily improve ovulation in women with obesity-related infertility

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8 Conclusion In conclusion, melasma is a chronic skin disorder with numerous etiologies including sun exposure and geographic environment, genetic predisposition, and also drug-induced and disease-induced hyperpigmentary skin disorders

However, recent evidence has shown that gut derived serotonin is capable of exerting multiple metabolic effects