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doi: 10.1016/j.amjms.2019.05.014 68 ChangHWLeeMLeeYSKimSHLeeJCParkJJet al

The kidney function measurements were done in 22 people with slower CYP1A2 variants who drank 3 cups or more of coffee a day, and the results were compared to 17 people with fast CYP1A2 variants who also drank 3+ cups a day.[ref] The kidney function measurements decreased faster over the course of 7 years in those with the slow CYP1A2 variants

Cells were washed and incubated with Cy-3 or Cy-5 conjugated secondary antibodies (Jackson ImmunoResearch Laboratories, West Grove, PA and Thermofisher)

10.1046/j.1365-2133.2002.4513_3.x 102 InomataS.TakadaK.TsunenagaM.FukudaM.MatsunagaY.AmanoS.et al (2003)

Conversely, another possibility is that a lower C4B copy number might protect the stability of the host microbiome to some extent by reducing the excessive clearance of beneficial microbes mediated by C4B

Novo Nordisk braces for generic challenge to Ozempic, Wegovy in China