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The inclusion of vitamin B3 in supplements or formulations is based on a metabolic theory of enhancement, which means it supports the production of cellular energy (ATP) and other metabolic processes rather than being primarily used for nausea (unlike niacin)

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I am still on the 7.5 mg for Zepbound and each time I go up in strength the nausea and diarrhea can come back pretty hard core but it only lasts the first week for me