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This nuclear localization in elderly Leydig cells correlated with reduced expression of 3-HSD, a crucial enzyme for testosterone synthesis, suggesting a link between nuclear FOXO4 and age-related decline in testosterone production [2]

Association of pharmacological treatments for obesity with weight loss and adverse events

Excessively low levels can cause a condition known as Laron Syndrome (dwarfism), which is usually diagnosed in childhood

Kothari A, White MG, Peacock O, Kaur H, Palmquist SM, You N, Taggart M, Salem U, Overman M, Kopetz S , Chang GJ

M.Whitaker-FornekJ

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