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Without sufficient B12, your body begins to form abnormally large blood cells that cannot perform, leading to fatigue, weakness, and other malaise
CYP3A4 inhibition by ketoconazole yielded an IC 50 of 0.83 M in iHLOs, comparable to HepaRG cells (0.42 M) but less potent than the IC 50 (0.056 M) from PHHs, demonstrating their applicability for studying CYP-mediated drug-drug interactions (Fig
T12M mean = 21.1 9.3 mol/L
Moreover, the design of MR studies avoids the potential risks and harms of exposure to antioxidants in a randomized controlled trial
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