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patients in studies 2 and 3 were on maximally tolerated metformin therapy

Conversely, aged cardiovascular systems might respond differently to the peptides multiple mechanisms, and these differences remain unstudied

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PMID: 22950504 6

FAKPaxillin Cascade Western blot analysis confirmed dose-dependent increases in phosphorylation of both FAK and paxillin, correlating with enhanced fibroblast migration and F-actin formation (Chang et al., Journal of Applied Physiology, 2011).

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