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Crown ethers are useful for dissolving ionic substances such as KMnO 4 in organic solvents such as isopropanol [(CH 3 ) 2 CHOH] (Figure 13.8 "Effect of a Crown Ether on the Solubility of KMnO")

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Metreleptin Metreleptin (MYALEPT) is an injectable human recombinant leptin analogue approved in Japan for metabolic disorders including lipodystrophy and in USA as first-line treatment for non-HIV related forms of generalized lipodystrophy (leptin deficiency, congenital/acquired lipodystrophy) (22)