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Who Should Consider GLP-1 Therapy FDA indications for weight loss require: BMI 30 (obesity), or BMI 27 (overweight) with at least one weight-related condition hypertension, type 2 diabetes, dyslipidemia, obstructive sleep apnea, cardiovascular disease, or similar These thresholds set eligibility, but they don't answer the more important question: who benefits most

Curcumin itself is the most active ingredient and appears to be the most important

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Front Chem 8:1086

The beneficial effects of GLP-1RAs on arrhythmias may be primarily mediated through their impact on CAD [37, 38]