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The overall prevalence of DA resistance is 10% for CAB and 20-30% for BRC

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Damage to the basement membrane and dermal structures

Harsh rubbing, especially on the face, can cause irritation and reduce comfort

While such reactions are uncommon, they require immediate medical attention

Also, an extension from stomach epithelium protection to stomach endothelium protection (and thereby concept background stomach endothelium stomach epithelium protection) (21-24) permits cytoprotective agents as an endothelium protectants class (although this was not originally claimed) (21-24), and consequently, application in thrombosis and bleeding disorders (5, 8, 25-28)