According to the NIH Office of Dietary Supplements, functional B12 deficiency is most commonly seen in patients with one or more of the following: Age over 50 stomach acid production declines with age, and stomach acid is required to free B12 from food PPI or H2 blocker use reflux medications suppress the acid needed for B12 absorption Metformin use, which interferes with B12 absorption directly Vegan or vegetarian diets B12 is found almost exclusively in animal products Gut conditions including celiac, IBS, SIBO, and Crohns MTHFR mutations that affect how B12 is metabolized once absorbed Heavy alcohol use The symptoms of low B12 are easy to dismiss: fatigue, brain fog, low mood, tingling in the hands or feet, weakness, and shortness of breath on mild exertion

Constipation on Tirzepatide or Semaglutide (GLP-1): A Step-by-Step MD Fix Joshua Silva, MD Jan 31 5 min read Updated: Feb 2 Medically authored by Joshua Silva, MD | Evidence-Based Weight Loss at Potere Health MD Definition Constipation on GLP-1 medications refers to infrequent, hard, or difficult-to-pass stools caused by medication-related slowing of gastrointestinal motility . The Quick Fix: How do I relieve constipation on GLP-1 medications
Following GLP-1 RA discontinuation, the patient experienced an increase in appetite, regained 7 kg (weight 167 kg, 79.4 kg/m 2 ) and was also later diagnosed with type 2 diabetes
Understanding which foods and nutrients have the strongest effect allows you to structure meals that naturally optimise this important metabolic hormone
The key differences: Saxenda (liraglutide) was the first GLP-1 medication approved specifically for weight loss and requires daily injections
It is important to understand these are not you over-the-counter medications