* P 0.05, ** P 0.01, *** P 0.001, and **** P 0.0001 by unpaired t test ( A C ), or 2-way ANOVA followed by Tukey post hoc tests ( D X )
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Instead of physically filling space, they work directly on blood sugar stabilization and neurotransmitter balance to turn off hunger signals
These differential effects may be attributed to their pharmacokinetic profiles and/or distinctions in how each peptide binds and activates the GLP-1R
