muscle cramps semaglutide TrimRX Does GLP-1 Cause Leg Cramps?

J Clin Endocrinol Metab 88 : 18041808 Viengchareun S et al

Cameron JC, Pakrasi HB

The cells were incubated with the respective probes in growth medium for the indicated time

GAPDH was used as a loading control ( n = 3).( B ) cAMP levels in coronary effluents were measured at timed intervals during an initial 10-minute perfusion of WT hearts with either 6 nM GLP-1(2836), scrambled(2836) control (Scram), or buffer-only control (Cntl), or with 0.3 nM GLP-1, and were normalized to coronary flow (mL/min/g heart weight)

PMID: 12587687

Ethics statement This study was carried out in strict accordance with the recommendations of the Guide for the Care and Use of Laboratory Animals of the Brazilian National Council of Animal Experimentation ( and the NIH Guidelines for the Care and Use of Laboratory Animals