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If the JNK inhibitors are not soluble at the target concentrations, the JNK inhibitors will be sterilized by either dry heat or gamma irradiation before being added to the sterile-filtered MCT

doi: 10.1073/pnas.1403215111 193 KimBYangM-SChoiDKimJ-HKimH-SSeolWet al

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It takes time, so do your best to stay consistent day in, day out