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These microbial alterations may be closely linked to disease activity, treatment response, and pathological mechanisms in SLE, providing a promising foundation for future microbiota-based diagnostic and therapeutic strategies (Table 1)

The late blight oomycete Phytophthora infestans was shown to activate a GST gene ( prp1-1 ) in potato

Inactivation of this gene has been described in up to 84% of class 2 uveal melanomas

After 5 years of monotherapy, 15% of individuals on rosiglitazone therapy, 21% of individuals on metformin therapy, and 34% of individuals on glyburide (glibenclamide) therapy had fasting glucose levels above the acceptable range (31)

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