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Prednisone, like other corticosteroids should not be administered concomitantly with: - Barbiturates, carbamazepine, phenytoin, rifampin or ephedrine: these drugs enhance the metabolism of corticosteroids reducing their therapeutic action

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And so, the best vitamin B12 forms are Adenosyl B12 and methyl B12 are the native forms of vitamin B12, bypassing several steps in the absorption cycle