do people gain weight back after tirzepatide loss maintenance discontinuing GLP-1 : r/Zepbound Can You Keep Weight Off

Health Canada explicitly warns that unauthorized injectable peptides bypass safety reviews and may contain contaminants, incorrect doses, undisclosed ingredients, and high-risk components

Participants had started injectable semaglutide or tirzepatide for obesity or type 2 diabetes and then discontinued treatment within three to 12 months

Risk increases with higher and more frequent use

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Linkage of GLP-1 into elastin-like protein (ELP) polymers that form viscous reservoirs at body temperature and methods for enzyme-controlled release of GLP-1 from reservoirs have also been described but have yet to receive clinical evaluation [44]