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(Jastreboff et al., NEJM, 2022) The 2025 head-to-head SURMOUNT-5 trial confirmed tirzepatide's superior metabolic effect across multiple endpoints in non-diabetic patients with obesity

Measured as absolute weight loss: 4.6 kg 0.6 kg vs 3.61 0.3 kg

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Available online at: (Accessed April 18, 2019)

Efficacy and safety of once-weekly tirzepatide in Japanese patients with obesity disease (SURMOUNT-J): A multicentre, randomised, double-blind, placebo-controlled phase 3 trial

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