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This may especially be the case for NENs, which express higher concentrations of growth factor receptors than normal cells, with preclinical studies showing that blockade of these receptors results in NEN cell growth inhibition and apoptosis [23,24]

Brilot, A

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*Correspondence: Xiaoyang Liu, [email protected]

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Materials and methods Cell culture and compound treatment HepG2 cells (ATCC, catalog: HB-8065) were cultured with 90% Eagles Minimum Essential Medium (EMEM, ATCC, catalog: 30-2003) and supplemented with 10% fetal bovine serum (FBS, Cytiva, catalog: SH30070.03) and 100 U/mL penicillin-100 g/mL streptomycin (Thermo Fisher Scientific, catalog: 15140122)