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Post-Exertional Malaise (PEM): Replenishing cellular glutathione levels provides the antioxidant buffer needed to protect tissues from the oxidative stress generated during physical or cognitive exertion, potentially raising the threshold for PEM

Cytochrome P450 IA2 activity in man measured by caffeine metabolism: effect of smoking, broccoli and exercise

Within experimental biochemical models, follistatin molecules are investigated for their ability to bind and modulate signalling molecules that influence cellular regulatory networks

Cavanaugh 1990

If you choose to consume more than one serving, ensure that total caffeine intake does not exceed recommended limits