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Adverse reactions related to hypotension (hypotension, orthostatic hypotension, and decreased blood pressure) were reported in 1.3% of semaglutide-treated patients versus 0.4% of placebo-treated patients during clinical trials of the semaglutide injection for weight management

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The combination of upregulated beta-3 receptors and sustained lipolytic signaling produces the highest rate of fat-specific weight loss during this period