While people who stayed on CargiSema over an 84-week span lost an average of 23% of their weight, they fared worse than people on Eli Lillys already approved drug tirzepatide, who saw an average of 25.5% weight loss
Even though the effects of SGLT2 inhibitors on blood pressure and weight loss in obese individuals without T2D are identical to those reported in T2D subjects, it is unknown whether such effects can also translate into reduced cardiovascular disease events in this study population
Most major payment processors and ad platforms require LegitScript certification before they'll work with a healthcare merchant in this space, and Google, Meta, and TikTok all gate GLP-1 and weight-loss-adjacent ads behind it
J Physiol Pharmacol 66(6):773778 [PubMed] Ma J, Hu X, Zhang W, Tao M, Wang M, Lu W (2025) Comparison of the effects of liraglutide, tirzepatide, and retatrutide on diabetic kidney disease in db/db mice
In some cases, taking the shot a day late might be a better strategy to ensure you feel your best during your scheduled activity
Another widespread myth claims that GLP-1s work slowly compared to other weight loss approaches