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Early findings indicate that its overall side-effect pattern shares similarities with other incretin-based therapies

Contact your GP within 2448 hours if heat intolerance significantly affects daily activities or if gastrointestinal symptoms persist

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However, many doctors prescribe Ozempic off-label for weight loss at much higher doses

Lowering Blood Sugar and Slowing Digestion Quieting Food Noise Lowering Body Weight Evidence also shows that medications like semaglutide, tirzepatide, and orforglipron are much more efficacious, meaning they lead to a higher total body weight loss more quickly than other medications that clinicians have historically prescribed to treat obesity, says Rekha Kumar, MD, associate professor of clinical medicine and attending endocrinologist at Weill Cornell Medical College in New York City