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Community oral doses (50-150 mg daily) are based on allometric scaling from mouse studies, oral bioavailability data, and several years of community trial and error

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doi: 10.1371/journal.pone.0079167 27 SzaboCColettaCChaoCModisKSzczesnyBPapapetropoulosAet al

To confirm that the observed phenotype was solely caused by the connection between the striatum and the SNcVTA region, we used the periaqueductal gray (PAG) region as an internal control

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