Membranes were isolated from the cell lysate by centrifugation at 55,000 rpm (~150,000 g ) using a Beckman TLA-55 rotor for 1 h at 4 C
3d), sustained plasma Exe4 concentrations and therapeutic effects were observed in DIO mice, owing to the compensatory high gene expression at the Alb gene in hepatocytes
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Moderate or severe gastrointestinal side effects were strongly associated with higher likelihood of discontinuation
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In turn, this may lead to vitamin B12 deficiency