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Over-the-counter lidocaine cream (4-5%) applied to the injection site 30-60 minutes before injection effectively numbs the skin

Pierce Christopher G, Uppuluri P, Tristan AR, Wormley FL Jr, Mowat E, Ramage G, Lopez-Ribot JL

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The side effects appear to be limited to mild, short-lived pain at the injection site

Insurance companies negotiate rebates with brand manufacturers, but uninsured patients face sticker prices that can exceed $1,200 per month for a single 4-week supply