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Return to drinking after treatment for SAH is high, with 6080% and 7080% of patients returning to drinking after 3 and 12 months, respectively [118]

Visible collagen-driven changes emerge from week 6 to 8 and compound over 4 to 6 months of consistent bi-weekly use

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Various structural alterations were made at the N-terminal such as substitution of D-norleucine for L-norleucine, N-acetylation of norleucine, and replacement of norleucine with GABA in order to improve overall stability by reducing susceptibility to aminopeptidases

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