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Improvements in blood sugar control, triglycerides, and systolic blood pressure stayed about the same after the reduced dosing
The compound's ability to restore tissue homeostasis and reverse age-related functional decline in animal models provides direct evidence for the role of senescent cells in aging processes, while its applications in cancer research offer insights into senescence mechanisms in disease progression and administration resistance
Furthermore, we observed a lethal embryonic phenotype for the gbh-1 loss-of-function strains, which was rescued upon L-carnitine supplementation
Kaufmann HJ, Taubin HL
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SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism
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