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The results indicate that FOXO4-DRI potently and selectively reduces the viability of senescent fibroblasts compared to non-senescent controls (2.7-fold and 1.7-fold difference for keloid and normal skin, respectively)

IC50: Concentration of inhibitor that cuts half of the activity of the enzyme

FASEB J 23(10):32633272 Song X, Long D (2020) Nrf2 and ferroptosis: a new research direction for neurodegenerative diseases

This has led to fewer rest days and a greater ability to stick to long-term fitness plans

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