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Dermatologic Common (1% to 10%): Hair loss, rash, urticaria Postmarketing reports : Alopecia, angioedema, rash, urticaria Hair loss was reported in up to 5.8% of treated patients vs 1% placebo, with higher incidence associated with greater weight loss (20% or more)

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Symptoms, which typically emerge before six months of age, include failure to thrive, decreased appetite, lethargy, anemia, and GI issues like diarrhea

It has been used extensively in animal studies, human cell models, and increasingly in off-label therapeutic settings, with minimal toxicity or organ stress reported

Monoclonal antibodies targeting ion channels and their therapeutic potential

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